About Us

At DNAstack, our mission is to power precision medicine by building software that breaks down barriers to responsible biomedical data sharing, discovery, and analysis. We build cutting-edge software and industry standards to help researchers and clinicians analyze sequencing data and make faster, more accurate diagnoses. Our platform supports national and international networks tackling rare disease, cancer, infectious disease, and more. We're a nimble, cross-functional team of scientists, engineers, designers, and product thinkers working at the intersection of genomics, software, and cloud technologies. Our mission is ambitious, and so is our team.

The Role

We're seeking a strategic and execution-oriented Senior Manager of Finance & Operations to lead our Finance and Operations team and serve as a key partner to our leadership team. This role will own the full spectrum of finance and operational functions—building the infrastructure and systems that enable sustainable growth.

As the Senior Manager of Finance & Operations, you'll be the architect of our operational excellence: translating raw data into actionable insights, building scalable processes, and ensuring we allocate resources strategically as we balance burn rate against growth ambitions. While the role currently balances finance and operations, it will naturally evolve to become more finance-focused as the company grows and operational processes mature. This is a high-impact role for someone who embraces ambiguity, thrives in dynamic environments and wants to shape the foundation of a growing technology company.

What You'll Do

Strategic Finance & Cash Flow Management

• Manage daily cash flow and maintain a 12-month rolling cash forecast, delivering monthly cash position updates with actionable recommendations
• Manage and coordinate relationships with external financial institutions and accounting firms to ensure secure, compliant asset management
• Maintain the capitalization table and equity administration to support fundraising readiness
• Review financial terms in customer contracts (MSAs) prior to signature, ensuring alignment with pricing, margins, and revenue recognition policies
• Support the executive team during fundraising activities by preparing financial materials and managing due diligence data rooms
  
  

Financial Planning & Analysis

• Own, maintain, and actively update the company’s financial model, including SaaS metrics (ARR, MRR, churn, CAC) and headcount planning
• Build and manage cross-functional budgets and resource plans in partnership with department leaders; advise executives on burn vs. growth trade-offs
• Analyze forecast vs. actual performance and deliver clear, executive-ready insights and recommendations
• Lead the annual budgeting process and quarterly reviews, tracking spend and enforcing cost controls
  
  

Accounting Operations & Compliance

• Manage end-to-end payroll processing, ensuring accuracy across compensation and benefits deductions
• Manage accounting for revenue, deferred revenue, and revenue accrual
• Oversee and review month-end accounting close (prepaids, fixed assets, accrued liabilities, monthly financial statement preparation, variance analysis), with executional support from our fractional bookkeeping team
• Process monthly accounts payable ensuring timely and accurate vendor payments
• Manage quarterly tax compliance (HST, EHT-annual) and lead execution of year-end filings, including corporate tax returns and SR&ED claims, in collaboration with external accounting firms
• Manage quarterly government claim prep and any other ad-hoc government claims/forms, including reporting and audits, with executional support from the People & Operations Associate
  
  

Business Operations

• Oversee hiring and recruitment processes, including talent acquisition and compensation planning, with day-to-day execution led by the People & Operations Associate
• Lead performance management processes, including merit cycles and role changes, with day-to-day execution led by the People & Operations Associate
• Oversee HR operations to ensure HRIS systems, employment contracts, and employee records remain accurate and compliant, with day-to-day execution led by the People & Operations Associate
• Oversee employee relations, professional development initiatives, and HR policy compliance with day-to-day execution led by the People & Operations Associate
• Manage annual business insurance policies, including renewals, audits, and coverage reviews to ensure appropriate risk protection and compliance
• Partner with department leaders on vendor procurement, contract negotiations, and renewals to optimize cost and compliance
• Oversee and support office operations and culture initiatives, including events and team-building, with day-to-day execution led by the People & Operations Associate
• Oversee equipment management, asset tracking, and third-party software usage meet privacy, security, and compliance standards, with day-to-day execution led by the People & Operations Associate
• Identify, implement, and operate scalable finance systems and AI-enabled tools to automate workflows, reduce manual effort, and improve operational efficiency
  
  

Skills

• Strong experience in financial planning and analysis, including budgeting, forecasting, variance analysis, cash flow management, and SaaS metrics (ARR, MRR, churn, CAC, LTV)
• Strong knowledge of accounting operations, including month-end close, payroll, audit readiness, and tax and government programs (e.g., SR&ED, grants)
• Experience managing external partners, including financial institutions, accounting firms, and vendors
• Excellent written and verbal communication skills, with the ability to engage senior leaders and translate financial and operational data into actionable insights
• Advanced proficiency in Excel and Google Sheets, with experience using accounting, HRIS/payroll, and financial planning systems
• Highly organized and operationally focused, with a strong process orientation and exceptional attention to detail.
• Strong collaboration and relationship-building skills
• Experience leveraging AI-enabled tools to automate workflows and improve productivity
• Experience in a SaaS, high-growth technology company, or startup is an asset but not required
  
  

Qualifications

• Bachelor’s degree in Finance, Accounting, Business Administration, Economics, or a related field, or equivalent professional experience
• 7–9 years of experience in finance or combined finance and operational role
• Canadian professional designations such as CPA (Canada), CFA or an MBA an asset but not required
  
  

Why This Role Is Exciting

• Impact: Be a foundational leader where your work directly shapes the company's trajectory as we scale
• Growth: Tremendous opportunity to build and scale as we grow—this role will evolve with the company
• Innovation: Work at the intersection of finance and AI, leveraging cutting-edge tools to drive operational excellence
• Mission-driven: Contribute to solving rare disease, cancer, and infectious disease challenges by enabling precision medicine
• Autonomy: High degree of ownership and decision-making authority with direct access to executive leadership
• Team culture: Join a collaborative, mission-driven team that values strategic thinking, continuous improvement, and intellectual curiosity

Where You'll Work

This role offers the flexibility of remote work, with the option to work in person from our Toronto office. This arrangement supports your needs and promotes a healthy work–life balance.

Eligibility

To be considered for this position, you must be eligible to work in Canada.

Benefits

• Remote friendly, with flexible hours and the opportunity to work on-site at our Toronto office
• Comprehensive health benefits: medical, dental and vision coverage for you and your dependents
• Three weeks vacation
• Unlimited sick days
• Maternity and parental leave top-up programs
• One-time remote office set-up stipend
• Career development and learning support
• Opportunity to participate in DNAstack's Employee Stock Option Program
• Opportunity to contribute to open science and global data-sharing efforts

The salary range for this role is $100,000 to $150,000. At DNAstack, we are dedicated to providing pay transparency to all candidates. Compensation at DNAstack is determined through various factors including but not limited to: comparable salary market data within Canada, technical skill assessment, a holistic view of previous work history, and internal pay equity with other DNAstack team members.

DNAstack is committed to fair and equitable compensation practices. In accordance with the appropriate legislation in each jurisdiction in which we operate, we ensure that our team members are compensated within equal pay ranges for work of equal value, regardless of gender.

We regularly review our compensation practices to identify and address any pay equity gaps. Our approach considers skill, effort, responsibility, and working conditions to ensure that compensation decisions are objective, transparent, and free from bias.

Pay equity is an ongoing process, and we are committed to maintaining compliance with legislative requirements while fostering a workplace that values fairness, respect, and inclusion.

At DNAstack, we are committed to building and fostering an inclusive, accessible environment for everyone. If you have any questions, concerns, or requests regarding accessibility needs at any stage of the interview process, please contact humanresources@dnastack.com and we will work with you to meet your needs.

As a small but mighty team, we use AI-powered tools to help us stay organized and efficient during our hiring processes. These tools help in areas such as sorting applications and highlighting matches to the role. These tools help us move faster, but they definitely don't make decisions for us - every application is reviewed by a real human on our team.

Your privacy matters to us. Any information you share is handled according to Ontario privacy laws as well as our internal privacy practices. If you have any questions about how we use AI in our hiring process, please reach out to humanresources@dnastack.com.

Note: this posting is for an existing vacancy that we are seeking to fill.

For compliance reasons, all offers of employment at DNAstack are conditional upon a successful background check that may consist of prior employment verification, reference checks, education confirmation, criminal background, or other information, as permitted by law.