Laboratory Technician (2 Positions Opened)

Specific Biologics

Specific Biologics

Toronto, ON, Canada
Posted 6+ months ago
Specific Biologics is dedicated to developing therapeutics that treat or cure diseases through precision gene editing. Our platform technology Dualase™ is uniquely designed to target and correct genetic errors in ways that better use a cell’s natural repair processes. Our technologies hold the promise to provide new and potentially curative treatments to patients with serious and life-altering genetic diseases.

Join us in our mission to treat or cure genetic diseases.

Laboratory Technician
Permanent, Full-time
On Site (Toronto, Ontario)

SUMMARY

Specific Biologics is seeking a highly motivated Laboratory Technician to join our start-up team. The core responsibilities of the Laboratory Technician will be to prepare research materials and reagents, as well as ensure smooth day-to-day operations of the lab. Preference will be given to candidates with a background in cell biology, molecular biology, biochemistry or related disciplines.

KEY RESPONSIBILITIES

· Support research and development experiments by preparing AAV, DNA, gRNA/mRNA, protein and chemical reagent stocks.
· Analytical testing to confirm quality of reagents.
· Perform routine cell culture maintenance including media preparation, seeding, feeding and splitting.
· Perform routine cell culture assays such as viability measurements, nuclear staining and other common cell culture techniques.
· Perform routine assays such as genomic extractions, PCRs and other molecular biology techniques.
· Perform routine cloning such restriction digestions, ligations, Sanger and full plasmid sequencing.
· Support the day-to-day functioning of the lab, such as material ordering, equipment maintenance, laboratory inventories, etc.
· Maintain organized and functional lab workspaces.
· Due to the nature of the work, occasional work may be required on weekends or holidays.

QUALIFICATIONS

· Diploma or university degree in Cell Biology, Molecular Biology, Biochemistry or related science discipline.
· Demonstrated experience working in a research laboratory, preferably in a pharmaceutical or biotech setting.
· Previous experience with laboratory information management systems (e.g. electronic lab notes and inventory management).
· Demonstrated experience or good working knowledge of current molecular biology techniques including (e.g. restriction digestions, PCR (including quantitative), analysis by gel electrophoresis, sanger sequencing, full plasmid sequencing, etc.)
· Demonstrated experience or good working knowledge in protein purification by chromatography (experience with AKTA systems is a plus).
· Demonstrated experience or good working knowledge of mammalian cell culture maintenance, including aseptic technique.
· Experience in AAV and mRNA production is a plus.
· Experience in preparing solutions, buffers and reagents, as well as ordering and organizing materials, supplies and equipment for laboratory use.
KEY SKILLS and ATTRIBUTES
· Self-motivated — eager to ‘dive-in’ and take ownership for work. Effectively manage time and plan activities.
· Collaborative and helpful — ability to work across functional areas – actively work with colleagues and take an active interest in other’s ideas and opinions.
· Organized – ability to set up and keep accurate and orderly records.
· Strong communicator — ability to explain complex, technical ideas to a variety of audiences. Clear, concise writing.
· Intellectual curiosity — desire to ask questions, challenge assumptions and develop unique solutions to challenging problems. Naturally drawn to researching new topics and approaches in literature and other sources.

WHAT WE OFFER

The role is performed on site at Specific Biologics’ labs in JLABS @ Toronto (661 University Ave, West Tower, Toronto). Specific Biologics benefit package offering includes:
· Participation in Employee Stock Option Plan (subject to board approval).
· Health, dental, life and accidental death insurance.
· Paid vacation.
· Paid sick leave.
GOOD TO KNOW
· Offers of employment are conditional upon the successful passing of a reference check and a background check as determined by JLABS @ Toronto policy, as well proof of post-secondary education.
· Due to the nature of the work and subject to applicable laws, Specific Biologics may in certain circumstances advise you that you are not permitted to work on a particular project without proof of immunization.

APPLICATION DETAILS

Applications will be accepted until September 15th, 2023, or until the position is filled. We thank all applicants for their interest. Only those candidates selected for an interview will be contacted.
Specific Biologics welcomes and encourages applications from people with disabilities. Accommodation is available on request for candidates taking part in all aspects of the selection process. Please advise us at any point and we will work with you to meet your needs.
Specific Biologics Inc. is committed to workforce diversity, creating equity across our systems and fostering and advancing a culture of inclusion. We know that bringing diverse backgrounds, cultures, and perspectives together drives innovation which helps us to solve today’s complex health problems. At Specific Biologics, we believe that diversity, equality and inclusion (EDI) is everyone’s responsibility and serves as a catalyst to enable everyone to reach their full potential and help us innovate to create a healthier world.