Company Description

UHN is Canada’s #1 hospital and the world’s #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.

UHN’s vision is to build A Healthier World and it’s only because of the talented and dedicated people who work here that we are continually bringing that vision closer to reality.

www.uhn.ca

Job Description

Union: Non-Union
Number of Vacancies: 1
New or Replacement Position: New
Site: Princess Margaret Research Tower
Department: Princess Margaret Cancer Centre
Reports to: Senior Scientist
Salary Range: $54,902 - $93,333 Per Year
Hours: 37.5 Hours Per Week
Shifts: Day shift
Status: Temporary Full-time
Closing Date: May 22, 2026

Position Summary:
The successful candidate will develop and apply computational approaches to integrate immunopeptidomics, rich multi-omics and clinical data to identify tumor-associated antigens and support personalized and off-the-shelf cancer vaccine design. The project will leverage patient tumor sample and patient-derived organoid/xenograft resources, advanced mass spectrometry-based immunopeptidomics, and RNA medicine platforms. The Postdoctoral Researcher will join a highly collaborative translational research environment at Princess Margaret Cancer Centre, with opportunities to work closely with other computational scientists, cancer biologists, clinicians, mass spectrometry experts, and RNA medicine teams.

Duties:

• Multi-omics data analyses to identify therapeutic targets
• Develop computational/deep learning methods for antigen discovery
• Develop tools for cancer vaccine design

Qualifications

• Awarded a PhD within the previous 5 years, or an MD or DDS within the previous 10 years
• PhD and advanced expertise in one or more of the following fields: computational biology, bioinformatics, genomics, computer science, statistics, cancer biology, and immunology
• Strong programming skills in Python and/or R are required
• Experience in any of the following areas is highly preferred: cancer genomics, single cell/spatial multi-omics integration, immunogenomics, proteomics or immunopeptidomics, machine learning, cancer vaccine/antigen discovery
• Please combine your Cover Letter & Resume into a single file before uploading

Additional Information

Why join UHN?

In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

• Competitive offer packages
• Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP https://hoopp.com/)
• Close access to Transit and UHN shuttle service
• A flexible work environment
• Opportunities for development and promotions within a large organization
• Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.

All applications must be submitted before the posting close date.

UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.

Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.

UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.

We thank all applicants for their interest, however, only those selected for further consideration will be contacted.